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胺碘酮、心律宁和普鲁卡因胺对缺血性室性心律失常疗效的比较研究
引用本文:张瑶,邹亚男,郝东侠,林惠先,肖杰宁. 胺碘酮、心律宁和普鲁卡因胺对缺血性室性心律失常疗效的比较研究[J]. 哈尔滨医科大学学报, 2005, 39(4): 344-345,348
作者姓名:张瑶  邹亚男  郝东侠  林惠先  肖杰宁
作者单位:1. 哈尔滨医科 大学第二临床医学院心内科,黑龙江,哈尔滨,150086
2. 哈尔滨医科大学 心血管病研究所,黑龙江,哈尔滨,150086
摘    要:目的探讨冠心病患者室性心律失常的有效治疗方法。方法通过动态心电图及12导联心电图观察胺碘酮、心律宁及普鲁卡因胺对冠心病室性心律失常的临床疗效。结果胺碘酮组疗效明显优于心律宁组及普鲁卡因胺组,经t检验证实有统计学意义(P〈0.05),且未发现明显副作用。结论胺碘酮治疗冠心病室性心律失常临床疗效较好,是一种较安全的药物治疗方法,临床可推广应用。

关 键 词:冠心病 室性心律失常 胺碘酮 心律宁 普鲁卡因胺
文章编号:1000-1905(2005)04-0344-02
收稿时间:2005-07-11
修稿时间:2005-07-11

Therapeutic effect of amiodarone compared with matrine and procainamide on ventricular arrhythmias in coronary heart disease
Zhang Yao;Zou YaNan;Hao DongXia;Lin HuiXian;Xiao JieNing. Therapeutic effect of amiodarone compared with matrine and procainamide on ventricular arrhythmias in coronary heart disease[J]. Journal of Harbin Medical University, 2005, 39(4): 344-345,348
Authors:Zhang Yao  Zou YaNan  Hao DongXia  Lin HuiXian  Xiao JieNing
Abstract:Objective To investigate an effectively therapeutic method for ischemic ventricular arrhythmias. Methods Compared the effect and safety of amiodarone, matrine and procainamide on ventricular arrhythmias in patients with coronary heart disease(CHD) by Holter and 12 leads electrocardiogram. Results In all groups, the occurrence of ventricular arrhythmias were reduced. There was a better effect in amiodarone group than the other two groups ( P < 0.05) . Conclusion There is an obvious therapeutic efficacy of amiodarone on ischemic ventricular arrhythmias. Amiodarone is better than matrine and procainamide in clinic.
Keywords:coronary heart disease    ventricular arrhythmias    amiodarone    matrine    procainamide
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