In vitro activities of anidulafungin and other antifungal agents against biofilms formed by clinical isolates of different Candida and Aspergillus species |
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| Authors: | Fiori Barbara Posteraro Brunella Torelli Riccardo Tumbarello Mario Perlin David S Fadda Giovanni Sanguinetti Maurizio |
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| Institution: | 1Institutes of Microbiology;2Infectious Diseases, Università Cattolica del Sacro Cuore, Largo F. Vito, 1, 00168 Rome, Italy;3Public Health Research Institute, New Jersey Medical School, UMDNJ, Newark, New Jersey |
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| Abstract: | We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC90s (SMIC90s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC90s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC90 values were obtained not only for amphotericin B and voriconazole but also for the echinocandins. |
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