心脑血管粥样易损斑块的诊断及研究进展

动脉粥样硬化易损斑块是指稳定性差及存在血栓形成倾向的斑块，急性心脑血管缺血事件主要是由易损斑块的破裂和继发血栓形成所致。研究表明，冠状动脉粥样硬化常与头颈动脉粥样硬化密切相关且常同时发生，一些炎症因子在发病早期即可在外周血中被检测到。诊断易损斑块的临床手段有很多，笔者就冠状动脉、头颈部血管粥样易损斑块的影像学诊断及相关血清炎症因子的研究现状与前景进行综述。

Diagnosis and research progress of atherosclerotic vulnerable plaque in the heart and brain

Atherosclerotic vulnerable plaque refers to the plaque with poor stability and tendency of thrombosis, and acute cardiovascular and cerebrovascular ischemia evens are mainly caused by the rupture of vulnerable plaque and secondary thrombosis. Studies have shown that coronary atherosclerosis is closed related to and often occurs simultaneously with head and neck atherosclerosis, and some inflammatory factors can be detected in peripheral blood at the early stage of the disease. There are many clinical method for the diagnosis of vulnerable plaque. In this paper, the imaging diagnosis of atherosclerotic plaque of coronary arteries and head and neck as well as the research status and prospects of related inflammatory factors are summarized as follows.