2型糖尿病患者胸椎椎体松质骨CT值与冠状动脉钙化的相关性分析

目的： 探究2型糖尿病（diabetes mellitus type 2，T2DM）患者单次冠状动脉螺旋CT扫描同时获取的胸椎椎体松质骨CT值与冠状动脉钙化数据的相关性。方法： 选取2018年7月至2019年11月期间行256排Revolution螺旋CT扫描的T2DM患者72例作为研究对象，并分为冠脉钙化阴性组与阳性组，分析两组患者临床资料、胸椎椎体松质骨CT值的差异，Spearman秩相关分析胸椎椎体松质骨CT值与冠状动脉钙化程度相关指标（累及分支数、严重程度）的相关性。结果： 冠状动脉螺旋CT扫描可一次性同步获取T2DM患者冠脉钙化数据及胸椎椎体松质骨CT值并完成一站式靶向分析。T2DM患者冠脉钙化阴性组和阳性组间年龄、性别、高血压史、糖尿病病程及胸椎椎体松质骨CT值差异有统计学意义（P＜0.05或P＜0.001）。T2DM患者胸椎椎体松质骨CT值与冠状动脉钙化累及分支数（rs=-0.748,P＜0.001）、严重程度（rs=－0.846,P＜0.001）呈显著负相关。结论： 在评估T2DM患者冠状动脉钙化严重程度与骨密度的关系时，可利用螺旋CT冠状动脉扫描同步获取胸椎椎体松质骨CT值反映患者骨密度，从而使患者避免多次接受辐射检查的风险，并节省了时间，降低了成本。

Correlation between CT value of thoracic vertebrae cancellous bone and coronary artery calcification in type 2 diabetes mellitus patients#br#

Objective To explore the correlation between CT values of thoracic cancellous bone and coronary artery calcification parameters in patients with type 2 diabetes mellitus (T2DM) during single coronary spiral CT scan. Methods Seventy two patients with T2DM who underwent 256 row Revolution spiral CT scanning from July 2018 to November 2019 were recruited as the study subjects and divided into negative and positive coronary calcification groups. The differences in clinical data and CT measurements of thoracic cancellous bone between the two groups were analyzed. Spearman rank correlation analysis was conducted to analyze the correlation between CT values of cancellous bone of thoracic vertebral body and the degree of coronary artery calcification (number of involved branches and severity). Results One time coronary spiral CT scan can synchronously obtain coronary calcification data and thoracic cancellous bone CT measurements in patients with T2DM, and complete one stop targeted analysis. There were significant differences in age, gender, history of hypertension, duration of diabetes and CT values of thoracic cancellous bone between negative and positive groups (P<0.05 or P＜0.001). CT values of thoracic cancellous bone in T2DM patients were significantly negatively correlated with the number of branches involved in coronary artery calcification (rs=-0.748, P<0.001) and severity (rs=-0.846, P<0.001). Conclusion In the assessment of the relationship between the severity of coronary artery calcification and bone density in T2DM patients, coronary spiral CT scan can be used to reflect the bone density of patients by simultaneously detecting the CT value of thoracic cancellous bone, which further helps T2DM patients avoid multiple radiation examinations and save time and money.