| 1,25二羟维生素D3的免疫调节及其在自身免疫性疾病中的研究进展 |
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| 引用本文： | 赖兰敏,彭桉平,陈曲波.1,25二羟维生素D3的免疫调节及其在自身免疫性疾病中的研究进展[J].中国免疫学杂志,2019,35(17):2169-2173. |
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| 作者姓名： | 赖兰敏 彭桉平 陈曲波 |
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| 作者单位： | 广州中医药大学第二临床医学院 |
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| 基金项目： | 广东省科技计划项目(2016A020215133);广东省科技计划项目(2016ZC0099);广东省中医院院内基金(YN2015MS12) |
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| 摘 要： | 1,25二羟维生素D31,25(OH)2D3]是人体内VitD3的活性形式,主要参与钙磷代谢。越来越多研究显示1,25(OH)2D3在免疫调节中发挥重要作用,其减少或缺乏与多种自身免疫性疾病相关,而补充1,25(OH)2D3可以有效预防和治疗某些自身免疫性疾病。本文就1,25(OH)2D3的免疫调节和在自身免疫性疾病的研究新进展作一综述。
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| 关 键 词： | 1 25(OH)2D3 免疫调节 自身免疫性疾病 |
Advances in immune regulation of 1,25 dihydroxy vitamin D3 and its research on autoimmune diseases |
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| LAI Lan-Min,PENG An-Ping,CHEN Qu-Bo.Advances in immune regulation of 1,25 dihydroxy vitamin D3 and its research on autoimmune diseases[J].Chinese Journal of Immunology,2019,35(17):2169-2173. |
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| Authors: | LAI Lan-Min PENG An-Ping CHEN Qu-Bo |
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| Institution: | (The Second Clinical College of Guangzhou University of Chinese Medicine,Guangzhou 510006,China) |
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| Abstract: | 1,25 dihydroxy vitamin D3 is an active form of VitD3 in human body,mainly involved in calcium and phosphorus metabolism.More and more studies have shown that 1,25 (OH) 2D 3 plays an important role in immune regulation,its reduction or absence is related to varieties of autoimmune diseases,and supplement 1,25 (OH) 2D 3 can effectively prevent and treat certain Autoimmune disease.This article reviews the recent advances in immunoregulation of 1,25 (OH) 2D 3 and studies in autoimmune diseases. |
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| Keywords: | 1 25 (OH) 2D 3 Immunoregulation Autoimmune diseases |
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