2010-2016年广州市户籍居民主要死因分析及对寿命损失的影响

目的 分析2010—2016年广州市户籍人口疾病死亡趋势变化对期望寿命及潜在寿命损失（PYLL）的影响,为政府制定疾病预防控制规划和政策提供依据。方法 对死因登记报告信息系统报告的2010—2016年广州市户籍人口死因监测资料进行分析,死因分类采用ICD-10中的死因分类标准进行编码及分析统计。通过死亡率、年度变化百分比、期望寿命、去死因期望寿命、减寿年数等指标进行分析,并描述疾病死亡变化对期望寿命和潜在寿命损失的影响。结果 2010—2016年广州市户籍人口死亡327 769例,平均死亡率为563.67/10万（标化率为327.19/10万）,以平均每年0.66％的速度上升。死因顺位前3位的是心脑血管疾病、恶性肿瘤、呼吸系统疾病,平均死亡率分别为204.61/10万、148.43/10万、88.99/10万。损伤中毒（伤害）、肌肉骨骼疾病和结缔组织疾病、内分泌营养代谢疾病死亡率平均每年上升11.54%,10.62%、5.53%。年平均PYLL为443 653人年,PYLL率为53.20‰,呈上升趋势。主要死因造成的PYLL的前3位分别是恶性肿瘤、心脑血管疾病、损伤中毒（伤害）,平均PYLL分别为177 631、88 302和58 678人年。结论 2010—2016年广州市户籍人口疾病死亡趋势变化对期望寿命影响从大到小依次为心脑血管疾病、恶性肿瘤、呼吸系统疾病。恶性肿瘤、心脑血管疾病和损伤中毒（伤害）等造成的潜在寿命损失逐渐加大。加强对这些慢性病的防治是广州市卫生工作的重点,尤其是预防恶性肿瘤的发生、提高其早诊早治对减少寿命损失有重要意义。

Leading causes of death and potential loss of life among residents in Guangzhou, 2010-2016

Objective To describe the impact of epidemiological trend of disease mortality on life expectancy and potential years of life loss （PYLL） among registered residents in Guangzhou from 2010 to 2016. Methods Surveillance data of causes of death of registered residents in Guangzhou from 2010 to 2016 were obtained from the Cause of Death Registration Information System. The classification of causes of death was coded and analyzed based on ICD-10. The mortality rate, life expectancy, and PYLL were analyzed and the impact of disease death on life expectancy and PYLL was described. Results The total deaths of registered residents were 327 769 in Guangzhou from 2010 to 2016, with a mean mortality rate of 563.67/100 000 （standardized rate, 327.19/100 000）, rising slowly at an annual average rate of 0.66%. The top three causes of death were cardiovascular and cerebrovascular diseases （204.61/100 000）, malignant tumors （148.43/100,000） and respiratory diseases （88.99/100,000）.The mortality rates of injury and poisoning, musculoskeletal and connective tissue diseases, and endocrine, nutritional and metabolic diseases increased by 11.54%, 10.62%, and 5.53% annually on average,respectively. The annual average PYLL was 443 653 person-years, with a PYLL rate of 53.20‰, showing an upward trend. The top three causes of death resulting in PYLL were malignant tumors, cardiovascular and cerebrovascular diseases, and injury and poisoning, with average PYLL of 177 631, 88 302 and 58 678 person-years, respectively. Conclusion The leading causes of death influencing the life expectancy were cardiovascular and cerebrovascular diseases, malignant tumors, and respiratory diseases among registered residents in Guangzhou from 2010 to 2016. The top three causes of death resulting in PYLL were malignant tumors, cardiovascular and cerebrovascular diseases, and injury and poisoning.