PET/CT和PET/MR在黑色素瘤中的临床应用及新进展

黑色素瘤易转移、复发率高，已经成为严重危及人民健康的恶性肿瘤之一，早期诊断和准确分期对预后及远期生存十分关键。18F-FDG PET/CT作为一项集PET与CT于一体的成像模式，被广泛地应用于包括黑色素瘤等在内的恶性肿瘤的诊断、分期及疗效的评估。随着一体化PET/MR成像系统研发的成功，多模态成像技术向前迈进了一大步，实现了真正意义上的数据同步采集。笔者就18F-FDG PET/CT及PET/MR在黑色素瘤分期、复发和疗效评价中的研究现状进行综述，介绍了多模态成像技术在黑色素瘤中的新进展。

Clinical application and new progress of PET/CT and PET/MR imaging in malignant melanoma

Malignant melanoma is prone to metastasis and recurrence. It has become one of the seriously health-threatening malignant tumors. Early diagnosis and accurate staging are very important for prognosis and long-term survival. 18F-FDG PET/CT is a novel imaging technique that combines the functional data of PET with the morphological information of CT. It has been widely used in the diagnosis and staging, local recurrence, and therapeutic response evaluation of malignant tumour including melanonma. With the successful clinical application of integrated-PET/MR imaging system, It has taken a great step forward in multi-modal imaging technology field, thereby realizing synchronous data acquisition. To understand new progress of multimodal imaging technology in malignant melanoma, this article provides a review of the value of 18F-FDG PET/CT and PET/MR in the staging, local recurrence, chemotherapy response evaluation of melanoma.