银川市儿童青少年体脂百分比腰围与心血管病危险因素的关联

目的分析银川市学龄儿童青少年体脂百分比(fat mass percentage,FMP)和腰围(waist circumference,WC)与心血管病危险因素的关联性,为防治儿童青少年心血管病发生提供依据。方法采用方便整群抽样的方法,抽取银川市1 043名12~18岁学龄儿童青少年,进行问卷调查、体格检查、体成分测定及生化检测。结果 FMP和WC均可预测儿童青少年发生血压偏高、高三酰甘油(TG)血症的风险(P值均<0.01),FMP和WC对心血管代谢异常的预测风险能力分别是心血管代谢正常组的1.14~2.36和1.32~2.09倍。FMP和WC结合对心血管病危险因素变异的解释(4.9%~22.1%)大于FMP或WC单独对其的解释(3.5%~22.0%),FMP对总胆固醇(TC)和低密度脂蛋白(LDL-C)的标准化回归系数(0.25和0.22)大于WC(0.17和0.14),FMP对收缩压(SBP),舒张压(DBP),TG,高密度脂蛋白(HDL-C)的标准化回归系数的绝对值小于WC。FMP肥胖联合WC肥胖组对血压偏高、高TG血症、高TC血症、低HDL-C血症和高LDL-C血症的预测风险分别是2个指标均正常组的3.67(95%CI=2.42~5.56)、3.09(95%CI=2.04~4.69)、3.37(95%CI=1.38~8.28)、2.00(95%CI=1.35~2.98)和4.73(95%CI=2.15~10.44)倍(P值均<0.01),高于其他不同组合对心血管病危险因素的风险预测。结论FMP和WC均可作为预测学龄儿童青少年心血管病危险因素的检测指标。建议将FMP与WC结合起来预测学龄儿童青少年罹患心血管疾病的风险。

Association of cardiovascular disease risk factors with fat mass percentage and waist circumference in children and adolescents in Yinchuan City

Objective To analyze the association between fat mass percentage(FMP) and waist circumference(WC) with cardiovascular risk factors in children and adolescents in Yinchuan City, and to provide a reference for preventing and contyolling the risk factors of cardiovascular diseases among children and adolescents. Methods A questionnaire survey, physical examination, body composition determination and biochemical tests were conducted among 1 043 children aged 12-18 years in Yinchuan selected through a convenient cluster sampling method. Results Among boys and girls, both FMP and WC were associated with high rate of high blood pressure and high TG in children and adolescents(P<0.01). The increased risk of metabolic abnormalities by FMP and WC were 1.14-2.36 times and 1.32-2.09 times, respectively. About 4.9%-22.1% of cardiovascular disease risk was explained by the combination of FMP and WC, which was significantly higher than separate interpretation of FMP or WC(3.5%-22.0%). Standardized regression coefficient for TC and LDL-C(0.25 and 0.22) was greater than WC(0.17 and 0.14) by FMP, and the absolute value of the standardized regression coefficient for SBP, DBP, TG, HDL-C was less than WC by FMP. The predictive risk for high blood pressure, high TG, high TC, low HDL-C and high LDL-C by combination of FMP and WC was 3.67(95%CI=2.42-5.56), 3.09(95%CI=2.04-4.69), 3.37(95%CI=1.38-8.28), 2.00(95%CI=1.35-2.98) and 4.73(95%CI=2.15-10.44) times higher than different combinations risk groups(P<0.01). Conclusion The ability of fat mass percentage and waist circumference to predict the risk of cardiovascular risk factors is similar. It might be used as a predictor of cardiovascular risk factors in children and adolescents. It is recommended to combine FMP with WC to predict the risk of cardiovascular disease among children and adolescents.