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Notch信号串话与肿瘤的关系
引用本文:马智勇,芮红兵.Notch信号串话与肿瘤的关系[J].按摩与导引,2012(14):42-43.
作者姓名:马智勇  芮红兵
作者单位:福建医科大学第一临床医学院,福州350000
摘    要:Notch信号通路在细胞分化发育过程中起重要作用,许多肿瘤形成都有Notch信号的参与。肿瘤的形成多是多因素共同完成的,研究发现Notch信号与Ras、Wnt、NF—kB、VEGF等的串话在肿瘤的发生、发展中发挥着协同或者拮抗的作用。本文就Notch信号的组成、活化及其串话 进行综述。

关 键 词:Notch  信号转导通路  信号串话肿瘤

Notch signal to crosstalk and its relationship with tumor
Ma Zhiyong Rui Hongbing.Notch signal to crosstalk and its relationship with tumor[J].Chinese Manipulation & Qi Gong Therapy,2012(14):42-43.
Authors:Ma Zhiyong Rui Hongbing
Institution:Ma Zhiyong Rui Hongbing
Abstract:Notch signaling pathway plays a key role in cell differentiation and proliferation, which involves the formation of many tumors. Many factors together lead to the formation of tumors, researches showed that the crosstalk between Notch signaling pathway and Ras, Wnt, NF-kB, VEGF played a synergistic or antagonistic effect in tumor occurrence and development. The composition of Notch signaling,activation and crosstalk are reviewed in the paper.
Keywords:Notch Notch signaling pathway Signal crosstalk Tumor
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