Neue Angaben zur chromosomalen Struktur des Sticker-Sarkoms

Zusammenfassung In allen den bisher untersuchten Fällen von Sticker-Sarkome des Hundes wurden die gleichen Chromosomenanomalien gefunden: 58–59 Chromosomen, darunter 13–17 metazentrische und 40–45 telozentrische. Ein beobachteter Tumor wies die doppelte Chromosomenzahl auf, auch die Zahl der metazentrischen Chromosomen machte etwa das Zweifache des bisher mitgeteilten Wertes aus. Dieser Chromosomensatz war auch in den Zellen von Transplantaten nachzuweisen. Es dürfte sich also um eine stabile polyploide Abart des Sticker-Sarkoms handeln.

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A new chromosomal variant of the Sticker venereal sarcoma

Summary In all earlier investigations of the Sticker venereal sarcoma in dogs identical chromosomal aberrations were found; there were 58–59 chromosomes of which 13–17 were metacentrics and 40–45 telocentrics. In the tumour presented here the karyotype was similar to that recorded previously except that the chromosome number was doubled; thus all the characteristic chromosomes were present in duplicate. The same duplicate chromosomal set was preserved when the tumour was transplanted to other dogs. Thus the tumour may be regarded as a stable polyploid variant of the Sticker venereal sarcoma.