The polymorphisms of various short tandem repeats on the Y chromosome in Japanese and German populations |
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Authors: | M Sasaki Rajvir Dahiya |
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Institution: | (1) Department of Urology (112F), VA Medical Center, UCSF, 4150 Clement Street, San Francisco, CA 94121, USA e-mail: view@itsa.ucsf.edu, Tel. +1-415-2214810 ext. 4553, Fax +1-415-7506639, US |
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Abstract: | In the present study we have analyzed the genotypes at the DYS389-I, DYS389-II, DYS390, DYS391, DYS393 and DYS19 loci on
the Y chromosome in Japanese and German populations. The genotypes were determined in the white blood cell DNA of 200 Japanese
and 111 German males. The 8-locus haplotype combination of these six loci with our previous data on DYS388 and DYS392 revealed
much lower maximum matching probability (0.0053 in Japanese and 0.0092 in Germans), much higher minimum diversity (dwmin) (0.9947 in Japanese and 0.9908 in Germans) and more haplotypes (194 in Japanese and 110 in Germans). These very high abilities
for discrimination could provide ideal tools for forensic analysis and population studies.
Received: 8 October 1998 / Received in revised form: 7 June 1999 / Accepted: 30 June 1999 |
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Keywords: | Short tandem repeat Y chromosome Population study |
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