| Toll样受体9与EB病毒感染研究进展 |
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| 引用本文： | 王佐凤,王强. Toll样受体9与EB病毒感染研究进展[J]. 国际儿科学杂志, 2011, 38(6): 598-601. DOI: 10.3760/cma.j.issn.1673-4408.2011.06.022 |
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| 作者姓名： | 王佐凤 王强 |
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| 作者单位： | 1. 646000,泸州医学院
2. 610072,四川省医学科学院 四川省人民医院儿科 |
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| 摘 要： | Toll样受体(Toll-like receptor,TLR)是新近发现的先天性免疫重要的跨膜受体和信号传导受体,通过免疫细胞表面的TLR,机体能够识别保守的病原相关分子模式,刺激细胞因子生成,上调抗原呈递细胞共刺激分子表达,活化T细胞,在先天性免疫与获得性免疫间建立一个紧密相连的桥梁.TLR9是TLR家族中的一员,主...
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| 关 键 词： | Toll样受体9 EB病毒 |
Progress of Toll-like 9 receptors in Epstein-Barr virus infections |
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| WANG Zuo-feng,WANG Qiang. Progress of Toll-like 9 receptors in Epstein-Barr virus infections[J]. International Journal of Pediatrics, 2011, 38(6): 598-601. DOI: 10.3760/cma.j.issn.1673-4408.2011.06.022 |
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| Authors: | WANG Zuo-feng WANG Qiang |
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| Abstract: | Toll-like receptor( TLR )is a newly discovered important innate immune receptor and signal transduction transmembrane receptor.By the TLR in the surface of immune cells,body can recognize conserved pathogen-associated molecular patterns,to stimulate the production of cytokine,increased costimulatory molecule expression of antigen-presenting cell,activating T cells,establishing a closely-linked bridge between the innate immunity and acquired immunity.TLR9 is a member of Toll-like receptor family,mainly identify viral or bacterial DNA containing unmethylated CpG dinucleotides.Studies have showed that TLR9 is in the immune system's recognition of EB virus,and it plays an important role in the infection and transformation of the EB virus.This paper reviews the studies of the interaction of TLR9 with EB virus. |
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| Keywords: | Toll-like receptors Epstein-barr virus |
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