休克期切痂植皮对小型猪烧伤后能量消耗的影响

目的 观察贵州三系实验用小型猪正常及烧伤后静息能量消耗(REE)的变化规律及休克期切痂植皮是否对烧伤后REE产生影响。方法借助小型猪烧伤模型，应用代谢车面罩法测量单位时间内氧气消耗量、二氧化碳产生量及REE的变化。结果 休克期切痂植皮组、非休克期切痂植皮组和单纯烧伤组伤后REE值均明显升高，但休克期切痂植皮组由于及时切痂植皮封闭创面，REE值在伤后96h开始下降，并于伤后12d内明显低于非休克期切痴植皮组和单纯烧伤组，而后两组则仍保持了持续的高代谢状态。结论 严重深度烧伤休克期切痂植皮可在一定程度上减轻机体的高代谢状态。

Effect of escharectomy and skin graftung of minipigs during burn shock stage on postburn energy expenditure

OBJECTIVE: To determine the changes in resting energy expenditure (REE) of minipigs in normal and postburn stage, and the effect of escharectomy during burn shock stage on energy expenditure. METHODS: Swine model with 35% TBSA III degree flame burn was used. Eighteen male minipigs were randomly divided into three groups: control group, escharectomy during burn shock stage group and escharectomy after burn shock stage group. REEs were monitored by means of Cardiorespiratory Diagnostic Systems (Medical Graphics Corporation, USA). RESULTS: The levels of REE in escharectomy during burn shock stage group decreased early and were obviously lower than those in other two groups. CONCLUSION: These findings suggest that escharectomy and skin grafting during burn shock stage could ameliorate hypermetabolism in major burn patients.