| NO在体外循环中脑损伤作用机制的研究进展 |
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| 引用本文： | 曹士奇,陈锁成,孙斌,郑世营.NO在体外循环中脑损伤作用机制的研究进展[J].医学综述,2007,13(16):1208-1210. |
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| 作者姓名： | 曹士奇 陈锁成 孙斌 郑世营 |
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| 作者单位： | 1. 江苏大学附属第一人民医院胸心外科,江苏,镇江,212002
2. 苏州大学附属第一医院胸心外科,江苏,苏州,215006 |
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| 基金项目： | 江苏省预防医学重大课题 |
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| 摘 要： | 一氧化氮及一氧化氮合酶在体外循环导致的脑损伤中具有重要作用,它可以通过扩张血管/抑制血小板聚集与黏附/减少细胞凋亡等对脑组织产生保护作用。一氧化氮的临床应用仍需对其作用机制作进一步深入研究。
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| 关 键 词： | 脑损伤 一氧化氮 一氧化氮合酶 体外循环 |
| 文章编号： | 1006-2084（2007）16-1208-03 |
| 收稿时间： | 2006-12-19 |
| 修稿时间： | 2006-12-192007-05-28 |
Study Progress of Nitric Oxide about its Mechanism in Brain Injury During Extracorporeal Circulation |
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| CAO Shi-qi,CHEN Suo-cheng,SUN Bin,ZHENG Shi-ying.Study Progress of Nitric Oxide about its Mechanism in Brain Injury During Extracorporeal Circulation[J].Medical Recapitulate,2007,13(16):1208-1210. |
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| Authors: | CAO Shi-qi CHEN Suo-cheng SUN Bin ZHENG Shi-ying |
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| Institution: | 1. Department Cardiothoracic Surgery, The First People s Hospital Affiliated to Jiangsu University, Zhenjiang 212002, China; 2. Department of Cardiothoracic Surgery, The First Hospital Affiliated to Suzhou UniversityI Suzhou 215006, China |
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| Abstract: | Nitric oxide(NO)and nitricoxide synthase(NOS)play an important role in brain injury caused by extracorporeal circulation,which has protective effects on brain damaged by broadening blood vessels or inhibiting platelet aggregation and adhesion as well as by reducing cell apoptosis.Clinical application of NO still needs further studying. |
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| Keywords: | Brain injury Nitric oxide Nitricoxide synthase Extracorporeal circulation |
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