肺部肠球菌医院感染的特点及耐药性分析

目的了解肺部肠球菌医院感染的特点及耐药情况.方法回顾性分析1998年1月～2003年12月期间我院74例肺部肠球菌医院感染者的临床资料及药敏结果.结果 74株肠球菌中粪肠球菌株(91.9%)多于屎肠球菌株(8.1%);老年,特别是慢性阻塞性肺疾病患者易发生肺部肠球菌医院感染;患者临床症状不典型,死亡率高(33.8%);肠球菌对多种抗菌药物耐药,对部分青霉素族和喹诺酮类抗生素耐药率低,对万古霉素和替卡西林敏感.结论肺部肠球菌医院感染防治困难,需根据药敏选用青霉素族或喹诺酮类抗生素,并严格掌握多肽类抗生素的适应证.

Enterococcal Hospital-acquired Infections in Lungs: Characteristic and Resistance Analysis

OBJECTIVE To investigate the characteristic of enterococcal hospital-acquired infection in lungs and drug sensitivity status of enterococci. METHODS Seventy four cases with enterococcal hospital-acquired infections in lungs and the resistance of enterococci were retrospectively analyzed. RESULTS From them the strains of Enterococcus faecalis (91. 9%) were more than E. faecium (8. 1%). Elders, especially those with chronic obstructive pulmonary diseases were more easily to be infected with enterococci in lung. The clinical symptoms were not typical and the mortality was high(33. 8%). Enterococci strains were resistant to multiple antibiotics, but sensitive to vancomycin and teicoplanin. the drug-resistance of enterococci to penicillins and quinolones was relatively lower. CONCLUSIONS It' s difficult to control enterococcal hospital-acquired infection in lungs. We' d better select penicillins and quinolones according the drug sensitivity status and restrict the use of vancomycin and other derivatives.