| 慢性活动性乙肝和重症乙肝血浆可溶性白细胞介素2受体(sTL—2R)的检测及其临床意义 |
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| 引用本文： | 严玉兰,张树林,陈太平,赵英仁,李义方,吴广利. 慢性活动性乙肝和重症乙肝血浆可溶性白细胞介素2受体(sTL—2R)的检测及其临床意义[J]. 滨州医学院学报, 1993, 0(2) |
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| 作者姓名： | 严玉兰 张树林 陈太平 赵英仁 李义方 吴广利 |
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| 作者单位： | 西安医科大学第一附属医院肝炎研究室，西安医科大学第一附属医院肝炎研究室，西安医科大学第一附属医院肝炎研究室，西安医科大学第一附属医院肝炎研究室，西安医科大学第一附属医院肝炎研究室，滨州医学院 研究生 |
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| 摘 要： | 本文以单克隆抗体ELISA夹心法对26例慢性活动性乙型肝炎(CAH-B)与40例重症乙型肝炎(SH-B)患者检测了血浆可溶性白细胞介素2受体(sIL-2R).结果提示CAH-B和SH-B患者血浆sIL-2R水平明显高于对照组(P<0.0005),SH-B的sIL-2R水平高于CAH-B(P<0.05);而急性重肝、亚急性重肝与慢性重肝三者之间血浆sIL-2R水平无显著性差异,提示血浆sIL-2R水平高低与肝脏损害严重程度明显相关.HBeAg阳性组与抗-HBe阳性组血浆sIL-2R水平无明显差别(P>0.05),这似乎说明血浆.sIL-2R水平高低与HBV复制状态无关.
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| 关 键 词： | 慢性活动性乙型肝炎 重症乙型肝炎 可溶性白细胞介素2受体 |
PLASMA LEVELS OF SOLUBLE INTERLEUKIN-2 RECEPTOR (sIL-2R) IN SEVERE AND CHRONIC ACTIVE HEPATITIS |
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| Wu Guangli,et al. PLASMA LEVELS OF SOLUBLE INTERLEUKIN-2 RECEPTOR (sIL-2R) IN SEVERE AND CHRONIC ACTIVE HEPATITIS[J]. Journal of Binzhou Medical College, 1993, 0(2) |
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| Authors: | Wu Guangli et al |
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| Abstract: | Plasma levels of sIL- 2R were measured by ELISA in 26 patients with chronic hepatitis B (CAH-B),40 patients with severe hepatitis B(SH-B) and 17 healthy controls.The levels of sIL -2R in patients with CAH-B and SH-B were found to be significantly elevated as compared with healthy controls (P <0. 0005). The level of sIL-2R in patients with SH-B was much higher than that in patients with CAH-B. These differences were independent of hepatitis B virus (HBV) replication,because there was no difference between HBeAg-positive patients and HBeAg -negative patients. |
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| Keywords: | chronic active hepatitis B severe hepatitis B soluble interleukin? receptor |
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