雷奈酸锶临床研究进展

目的 对抗骨质疏松药物雷奈酸锶的整个研究过程进行分析,评价其各阶段研究的有效性.方法 简要总结雷奈酸锶各个阶段研究试验情况,系统概括近10年来雷奈酸锶的研究结论.结果 雷奈酸锶具有双重抗骨质疏松作用,能够有效地预防骨质疏松患者骨密度下降,显著降低骨质疏松骨折发生危险.结论 口服雷奈酸锶是治疗骨质疏松症的一种有效办法,应当成为抗骨质疏松治疗的一种新选择.

Advance in Clinic Research for Strontium Ranelate

Objective To summarize the study process of the anti-osteoporosis agent, strontium ranelate, and evaluate the effectiveness of strontium ranelate in each study stage. Methods Experimental status of strontium ranelate in each study stage was overviewed, and study conclusions of strontium ranelate published in recent ten years were summarized. Results Strontium ranelate has dual effects of bone formation induction and bone resorption reduction. This treatment with strontium ranelate could prevent the reduction of bone mineral density （BMD）, and significantly decrease the risk of osteoporotie fracture. Conclusion Strontium ranelate is an efficient treatment of osteoporosis, and should be considered as a new choice.