综合心理行为干预对首发精神分裂症患者康复效果的影响

目的：探讨综合行为干预对首发精神分裂症患者社会功能和生活质量康复效果的影响。方法将60例首发精神分裂症患者采用随机数字表法分为干预组和对照组，每组30例，对照组在常规应用利培酮治疗的同时给予精神科基础护理，干预组在此基础上实施综合行为干预。采用阳性和阴性症状量表（PANSS）、简明精神病评定量表（BPRS）评定疗效；社会功能缺陷筛查量表（SDSS）评定患者的社会功能；生活满意度量表（SWLS）评定患者的生活质量；大体评定量表（GAS）评定患者的大体病情。比较两组患者护理干预前、干预后6周末、12周末和18周末各量表评分。结果实施综合行为干预措施后干预组患者的PANSS 总分为（17．90±4．20）分，其中阳性症状为（8．67±2．77）分、阴性症状为（9．30±2．78）分，一般精神病理症状为（20．80±4．25）分，均低于对照组，差异有统计学意义（ t分别为7．74，5．32，5．90，3．72；P＜0．01）；SDSS评分为（13．80±3．99）分、SWLS评分为（15．43±4．01）分、BPRS＆amp;nbsp；评分（22．63±4．15）分也均低于对照组，GAS评分为（78．00±14．42）分高于对照组，差异均有统计学意义（t分别为4．85，7．41，5．77，6．83；P＜0．01）。结论综合行为干预措施有助于改善首发精神分裂症患者的精神症状，提高患者的社会功能和生活质量。

Effect of comprehensive psychological interventions on social functions and quality of life of patients with the first-episode schizophrenia

Objective To explore the effect of comprehensive nursing interventions on social functions and quality of life of first-episode schizophrenic patients .Methods Sixty patients with first-episode schizophrenia were randomly divided into intervention group and control group （30 patients for each group）.All patients were treated with risperidone and basic psychiatric nursing care .Besides, the intervention group was given comprehensive nursing interventions additionally .Positive and Negative Symptoms Scale （ PANSS ） was used to evaluate the efficacy; Social Disability Screening Schedule （ SDSS ） was used to evaluate the social functions;Satisfaction with Life Scale （ SWLS） was used to evaluate the quality of life and Global Assessment Scale（GAS） was used to evaluate the general condition .PANSS, SDSS, SWLS and GAS were used to survey all the patients before and at the 6th, 12th and 18th week after the nursing interventions .Results At the end of 6th, 12th and 18th week after the nursing interventions, the total score of the PANSS was （17.90 ±4.20）, including positive symptoms score of （8.67 ±2.77） and negative symptoms score of （9.30 ±2.78）.The general mental state score was （20.80 ±4.25）.The differences between groups were significant （t=7.74, 5.32, 5.90, 3.72, respectively;P＆lt;0.01）.The scores of SDSS, SWLS, BPRS and GAS for the intervention group were （13.80 ±3.99）,（15.43 ±4.01）,（22.63 ±4.15） and （78.00 ±14.42）, which were significantly lower than those in the control group （t=4.85, 7.41, 5.77, 6.83, respectively;P〈0.01）.Conclusions Comprehensive nursing interventions can not only help patients improve psychiatric symptoms , but also improve the social functions and the quality of life of the patients with first-episode schizophrenia .