麻黄附子细辛汤联合腰四味治疗老年性腰腿痛70例

目的:观察麻黄附子细辛汤联合腰四味加减治疗老年性腰腿痛的近期疗效。方法:将137例患者随机按数字表法分为观察组70例和对照组67例。对照组服用杜仲壮骨胶囊,4粒/次,3次/d。观察组采用麻黄附子细辛汤联合腰四味加减,1剂/d。两组疗程均为4周。进行治疗前后简式疼痛问卷表(SF-MPQ)评分,腰痛Oswestry功能障碍指数问答表(ODI),世界卫生组织生存质量量表简表(WHOQOL-BREF),日常生活能力量表(ADL)和肾阳不足,寒湿痹阻证辨证评分。结果:治疗后两组SF-MPQ各维度评分均比治疗前下降(P0.01),观察组SF-MPQ各维度评分均低于对照组(P0.01);治疗后观察组ODI和肾阳不足,寒湿痹阻证辨证评分均低于对照组(P0.01),ADL评分上升幅度高于对照组(P0.01);治疗后观察组WHOQOL-BREF生理、心理、社会关系3个维度及总分均高于对照组(P0.01);两组治疗前后环境维度评分变化无统计学意义。结论:麻黄附子细辛汤联合腰四味加减能减轻老年性腰腿痛患者的疼痛,改善病情,提高患者生活能力和生活质量,近期治疗疗效明显。

Addition and Subtraction of Mahua Fuzi Xixin Tang Combined With Yaosiwei in Treating 70 Cases With Senile Lumbocrural Pain

Objective: To observe the short-term effects of addition and subtraction of Mahua Fuzi Xixin Tang combined with Yaosiwei in treating senile lumbocrural pain. Method: Totally 137 patients were divided into the control group (67 cases) and the observation group (70 cases) by random number table. The control group took Duzhong Zhuanggu capsules, 4 grains/time, 3 times/day. The observation group received the therapy of addition and subtraction of Mahua Fuzi Xixin Tang combined with Yaosiwei, 1 dose/day. The courses of treatment were 4 weeks in both groups. Before and after the treatment, short form-McGill pain questionnaire (SF-MPQ), Oswestry disability index (ODI), World Health Organization's quality of life questionnaire-Brief version (WHOQOL-BREF), activity of daily living (ADL) and scores of kidney yang insufficiency and cold dampness syndrome were measured. Result: Before and after the treatment, both groups showed declines in all SF-MPQ dimensions (P<0.01).All SF-MPQ dimensions in the observation group were lower than that in the control group (P<0.01). After the treatment, the scores of SF-MPQ, ODI, kidney yang insufficiency and cold dampness syndrome in the observation group were lower than that in the control group (P<0.01), with a higher growth in ADL score than the control group (P<0.01). After the treatment, the observation group showed higher WHOQOL-BREF scores in physical, psychological and social dimensions and total score than the control group (P<0.01), but with no statistical significance in differences in environment scores between the two groups. Conclusion: Addition and subtraction of Mahua Fuzi Xixin Tang combined with Yaosiwei can relieve pain of patients with senile lumbocrural pain, ameliorate their conditions and improve their viability and quality of live, with an obvious short-term effect.