Human follicular fluid from pre-ovulatory follicles in patients undergoing in-vitro fertilization inhibits the in-vitro growth of Gram-positive micro-organisms |
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| Authors: | Gurgan, T. Urman, B. Diker, K.S. Delilbasi, L. Kisnisci, H.A. |
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| Affiliation: | Department of Obstetrics and Gynaecology, IVF—ET Unit, University of Hacettepe, Faculty of Medicine Ankara, Turkey 2Department of Microbiology, University of Ankara, Faculty of Veterinary Medicine Ankara, Turkey 3Department of Histology and Embryology, University of Hacettepe, Faculty of Medicine Ankara, Turkey |
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| Abstract: | In this study, we assessed the antibacterial activity of humanfollicular fluid obtained from patients undergoing oocyte aspirationfor in-vitro fertilization and embryo transfer. Gram-positiveand Gram-negative microorganisms and Candida albicans were addedto the follicular fluid and broth cultures which served as controls.Follicular fluid was shown to be inhibitory against Gram-positivemicroorganisms; this inhibition was probably due to lysosymeand progesterone. Growth of Gram-negative micro-organisms andC.albicans were, however, supported by follicular fluid incubation. |
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| Keywords: | antimicrobial activity/follicular fluid/IVF |
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