应用自体静脉套和脑细胞生长肽对面神经损伤恢复影响的临床研究

目的研究采用自体静脉管套入吻合口并注入脑细胞生长肽的方法,对面神经损伤后功能恢复的影响.方法吻合神经断端后用自体静脉管套入吻合口并注入脑细胞生长肽.分析肌电图和观察表情肌功能恢复,比较两种方法对损伤的面神经功能恢复的影响.结果自体静脉管套入吻合口并注入脑细胞生长肽的方法,比传统方法表情肌功能恢复时间明显缩短,且一期修复比二期修复功能恢复时间明显缩短,差异具有非常显著性意义(P＜0.01).两种方法修复面神经损伤,表情肌功能恢复后检测面神经传导速度差异无显著性意义(P＞0.05).结论自体静脉管套入吻合口并注入脑细胞生长肽的方法是一种比较有前途的面神经修复方法.

The effect of autogenous vein cuff and injection of cerebral cell growth peptide on the recovery of injured facial nerve

Objective To study the effect of autogenous vein cuff and injection of cerebral cell growth peptide on the recovery of the injured facial nerve. Methods The injured facial nerve was anastomosed and covered with an autogenous vein cuff. Cerebral cell growth peptide was then injected to it. The different repairing methods were evaluated and compared with electromyography and observing functional recovery of the mimetic muscles. Results The new repairing method accelerated the recovery of the injured facial nerve. The recovery period of mimetic muscle function was significant shorter than the traditional method (P<0 01). The recovery period of I-stage repairing was significant shorter than that of II-stage repairing (P<0 01). The conduction velocity of the repaired facial nerves had no obvious differences between the new repairing method and the traditional method (P>0 05). Conclusion Application of the autogenous vein cuff to cover the nerve anastomosis and injection of cerebral cell growth peptide is a promising method for facial nerve repairing.;