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Macrocephaly and epidural involvement of T-cell acute lymphoblastic leukemia |
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| Authors: | Jaing Tang Her Hung Po Cheng Hung Iou Jih Wang Huei Shyong Wang Chao Jan |
| Affiliation: | * Hematology/Oncology; Department of Pediatrics; Chang Gung Children’s Hospital;, Taoyuan, Taiwan † Neurology; Department of Pediatrics, Chang Gung Children’s Hospital, Taoyuan, Taiwan ‡ Department of Diagnostic Radiology; Chang Gung Children’s Hospital;, Taoyuan, Taiwan |
| Abstract: | We describe a 2-year-old female who presented with macrocephaly and anemia. Magnetic resonance imaging revealed a diffusely enhancing epidural lesion over the sagittal frontoparietal region. Bone marrow examination confirmed the diagnosis of T-cell acute lymphoblastic leukemia. Induction chemotherapy led to hematologic remission and neuroimaging resolution of the mass. This report suggested macrocephaly could be a rare and early manifestation of leukemia in children. |
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