腮腺动态显像评价鼻咽癌放疗对腮腺功能的影响

目的 探讨腮腺动态显像评价鼻咽癌放疗对腮腺功能影响的价值。方法 21例鼻咽癌患者分别于放疗前、后行放射性核素腮腺动态显像,计算腮腺摄取指数(UI)、酸刺激后的分泌率(ER)、分泌指数(EI)等半定量指标以评价放疗前后腮腺功能的变化。结果 放疗后与放疔前比较,所有患者UI、ER、EI均显著下降,t值分别为56.65、41.34、30.69,P<0.001,腮腺摄取与分泌功能均明显受损,与患者临床口干症状相符。结论 腮腺动态显像是一种评价鼻咽癌放疗对腮腺功能的影响的有用方法,具有临床应用价值。

Evaluation of parotid function using dynamic parotid scintigraphy in nasopharyngeal carcinoma patients treated with external beam radiation therapy

Objective To evaluation of the parotid function using dynamic parotid scintigraphy in nasopharyngeal carcinoma patients treated with external beam radiation therapy. Methods Twenty-one nasopharyngeal carcinoma patients were included into this study. Dynamic parotid scintigraphy was performed before and after external beam radiation therapy. Semi-qnantitative parameters of parotid (uptake index, excretion rate and excretion index) was used to evaluate the changes of parotid function. Results UI, ER and El of parotid were decreased markedly after external beam radiation therapy, t is 56.65, 41.34, 30.69 respectively, P<0.001. The uptake and excretion function of the parotid were all impaired, which correlated with the dry mouth symptom of the patients. Conclusion Dynamic parotid scintigraphy can play a key role in the evaluation of parotid function in nasopharyngeal carcinoma patients treated with external beam radiation therapy.