Identification of the hypervirulent lineages of Neisseria meningitidis,the ST-8 and ST-11 complexes,by using monoclonal antibodies specific to NmeDI |
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| Authors: | Claus Heike Weinand Hanne Frosch Matthias Vogel Ulrich |
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| Affiliation: | Institute for Hygiene and Microbiology, University of Würzburg, Würzburg, Germany. |
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| Abstract: | Most cases of serogroup C meningococcal disease are caused by the clonal lineages ST-8 and ST-11. The gene encoding the putative restriction-modification system NmeDI is specific to these lineages. We report here a monoclonal antibody directed against the NmeDI endonuclease as a tool for their rapid and spe-cific identification. |
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