不同眼轴眼振荡电位与糖尿病视网膜病变眼振荡电位相关性研究

目的比较不同眼轴眼振荡电位与糖尿病视网膜病变（DR）眼振荡电位幅值的相关性,研究不同眼轴患者视网膜微循环功能的变化。方法回顾性收集不同眼轴患者32例（32只眼）进行视网膜电流图检查,同时收集经荧光素眼底血管造影证实的Ⅲ期及Ⅳ期DR患者18例（30只眼）进行视网膜电流图检查,比较不同眼轴眼振荡电位与DR患者振荡电位的相关性。结果正常眼轴眼平均∑O为（143.81±42.47）μv,中等眼轴眼平均∑O为（93.93±28.93）μv,长眼轴眼平均∑O为（68.43±17.99）μv;Ⅲ期DR平均∑O为（108.19±21.21）μv,Ⅳ期DR平均∑O为（69.70±16.63）μv。比较5组之间的差异有统计学意义（F=16.896,P〈0.01）,中等眼轴患者∑O值与Ⅲ、Ⅳ期DR患者∑O值差异无统计学意义,长眼轴患者∑O值与Ⅲ期DR患者∑O值差异有统计学意义,与Ⅳ期DR患者∑O值差异无统计学意义。结论随着眼轴的逐渐增长,视网膜振荡电位逐渐下降。长眼轴患者视网膜的微循环功能低于Ⅲ期DR患者。

Relationship of oscillatory potential between different axial length eyes and diabetic retinopathy eyes

Objective To compare the relationship of oscillatory potential between different axial length eyes and diabetic retinopathy eyes,investigate the change of retinal microcirculation in different axial length eyes.Methods This was a retrospective study.32 patients（32 eyes） with different axial length was collected to do electroretinogram,at the same time 18 patients（30 eyes） who was diabetic retinopathy proved by fundus fluorescein angiography was collected to do electroretinogram.Compare the relationship of oscillatory potential between two kind of eyes.Results ∑O of oscillatory potential in normal axial length was（143.81 ± 42.47） μv,in moderate eyes it was（93.93 ± 28.93） μv,in long eyes it was（68.43 ±17.99μv） ;∑O in Ⅲ stage of diabetic retinopathy was（108.19 ±21.21） μv,in Ⅳ stage of diabetic retinopathy it was（69.70 ± 16.63μv）.There was statistical significance of those five group（F = 16.896,P 0.01）.∑O of moderate eyes had no statistical significance with diabetic retinopathy either Ⅲ stage or Ⅳ stage;∑O of long eyes had statistical significance with Ⅲ stage diabetic retinopathy,however there was not statistical significance between long eyes and Ⅳ stage diabetic retinopathy.Conclusion With the growth of axial length,oscillatory potential was fall-off.Retinal microcirculation in patients who were long eyes is lower than the patients in Ⅲ stage diabetic retinopathy.