某企业二甲基甲酰胺接触人群肝功能损伤的流行病学分析

目的通过分析某企业接触二甲基甲酰胺(DMF)人群肝功能损伤的流行病学情况,为预防职业病的发生提供对策和依据。方法采集某企业职工空腹静脉血测定肝功能各项指标,并对2010—2011年某企业接触二甲基甲酰胺工人健康检查资料进行统计分析。结果 2010年和2011年肝功能异常率分别为40.25%和32.17%,接触二甲基甲酰胺人群在性别、年龄组之间肝功能异常率差异无统计学意义,但工作年限之间差异有统计学意义。结论应加强二甲基甲酰胺接触人群的管理,定期进行职业健康检查,早发现、早治疗,预防职业病的发生。

Epidemiological analysis of Liver function damage in workers exposed to dimethylformamide

Objective]Through epidemiological analysis of hepatic injury of workers exposed to DMF in a enterprise,to provide countermeasures and evidence for prevention of occupational diseases.Methods]Venous blood of workers were collected to determine indicators of liver function.Statistic analysis was conducted on the examination data of workers exposed to DMF from 2010-2011.Results]The abnormal liver function rate of 2010 and 2011 was 40.25% and 32.17% respectively,the differences between workers with different gender and age were not significant,but significant between service length.Conclusion]It is necessary to strengthen the management of workers exposed to DMF,to conduct regular occupational health screening so as to achieve the goals of early detection,early treatment and prevention of occupational diseases.