Dopamine-dependent contralateral circling induced by neurotensin applied unilaterally to the ventral tegmental area in rats |
| |
| Authors: | Larry J. Holmes Roy A. Wise |
| |
| Affiliation: | Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University 1455 Boulevard de Maissoneuve, Montreal, Quebec H3G 1M8 Canada |
| |
| Abstract: | Unilateral application of neurotensin (5, 10, and 15 micrograms) to the ventral tegmental area in rats caused contralateral circling. Pretreatment with pimozide (0.5 mg/kg) blocked the behavior. As is the case with circling elicited by unilateral ventral tegmental morphine, the diameter of the circles made by the animals was determined by environmental factors rather than by internal motor programming. |
| |
| Keywords: | Neurotensin Circling Ventral tegmental area Dopamine |
| 本文献已被 ScienceDirect 等数据库收录！ |
