氨酚羟考酮与塞来昔布对军队训练伤镇痛的疗效观察

目的观察塞来昔布与氨酚羟考酮2种镇痛药物对军队训练伤的镇痛效果以及安全性,为军队训练伤的镇痛用药提供可靠依据。方法将90例训练伤伤员分为3组,每组30例,分别使用塞来昔布、氨酚羟考酮以及安慰剂镇痛,在用药前及用药后第2、4、6、8天进行VAS疼痛评分,观察对比其药物疗效以及安全性。结果塞来昔布在各个时间点的VAS评分均小于氨酚羟考酮组,且不良反应较氨酚羟考酮轻或无,差异均有统计学意义(P0.05)。结论塞来昔布相比氨酚羟考酮的镇痛作用更为显著,且不良反应少,安全性高,应为军队训练伤镇痛的首选药物。

Observation on analgesic effect of oxycodone acetaminophen and celecoxib for military training injury

Objective To investigate the analgesic effect and safety of oxycodong acetaminophen and celecoxib on the military training injury, and provide a reliable evidence for the usage of drugs. Methods 90 patients were randomly divided into 3 groups （ n = 30）, which were celecoxib group,nxycodone acetaminophen group and placebos group. The efficacy and safety were evaluatedv by the visual analogue score （VAS） before using the drug and the 2nd day,4th day,6th day,8th day after giving drugs. Results The VAS of celecoxib group at each time point were less than that of oxycodong aeetaminophen group. And there were nearly no adverse reactions of celecoxib group. The differences were statistically significant （P 〈 0.05 ）. Conclusion The celecoxib has a good analgesic effect on military training injury and less adverse reactions. Which should be the first choice for paitents suffering from the pain of military training injury.