肝部分切除患者术后并发感染的相关影响因素分析

目的探讨肝部分切除患者术后感染的影响因素,为预防肝切除术后感染的发生提供理论依据。方法回顾性分析2007年12月至2012年12月210例诊断为肝癌行肝部分切除患者的临床资料,将其分为感染组和非感染组,比较2组相关临床资料,采用logistic逐步回归法进行统计学分析,筛选影响术后感染的关键性变量。结果肝部分切除术后有30例感染,感染率为14.3%。患者的年龄、手术时间、失血量、有无输血及有无肝硬化,2组比较差异均有统计学意义(P0.05)。logistic回归分析显示,患者的年龄、手术时间、失血量、有输血及肝硬化是肝部分切除术后感染的关键危险因素。结论年龄大于等于60岁、手术时间大于等于5 h、失血量大于等于3 000 mL、有输血及合并肝硬化是肝部分切除术后感染并发症的关键危险因素。

Risk factors of infections in hepatic cancer patients after partial hepatectomy

Objective To investigate risk factors of infections in hepatic cancer patients after partial hepatectomy so as to provide theo- retical basis for the prevation of infections after the hepatecomy. Methods A total of 210 patients who underwent partial hepatectomy from December 2007 to December 2012 were divided into the infection group and the non-infection group, and they were retrospectively reviewed. Multivariate analysis was performed with logistic regression test. Results Totally 30 patients were infected after operation, and the incidence of infection was 14.9%. There were singinficant difference between age,operation time,blood loss ,blood transfusion and cirrhosis in the two groups（P 〈 0.05 ）. Multivariate logistic regression analysis showed that the age, operation time, blood loss, blood transfusion and cirrhosis were significant risk factors for the infections after partial hepatecomy. Conclusion Aged over 60 years, operation time more than 5 hours, blood loss more than 3 000 mL, blood transfusion and cirrhosis were the key risk factors for the infections after partial hepatecomy.