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OUTBREAK OF CO-TRIMOXAZOLE- and GENTAMICIN-RESISTANT KLEBSIELLA AEROGENES BACTEREMIA IN NEUTROPENIC PATIENTS RECEIVING ORAL CO-TRIMOXAZOLE PROPHYLAXIS
Authors:M. F. LEAHY  M. W. HUMBLE
Affiliation:Senior Lecturer in Hematology, Wellington Clinical School of Medicine, Wellington Hospital, Wellington 2, New Zealand;Senior Lecturer in Microbiology. Department of Pathology. Wellington Clinical School of Medicine. Wellington Hospital, Wellington 2, New Zealand
Abstract:Over a five-day period, three neutropenic patients developed bacteremia with an identical strain of Klebsiella aerogenes (serotype K16) resistant to co-trimoxazole and gentamicin. All three patients had received prophylaxis with oral co-trimoxazole before the onset of bacteremia. This report outlines some of the problems associated with co-trimoxazole prophylaxis. (Aust NZ J Med 1983; 13: 636–638.)
Keywords:Co-trimoxazole    prophylaxis    neutropenia    Klebsiella bacteremia.
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