弥漫性泛细支气管炎误诊4例临床分析

[目的]探讨弥漫性泛细支气管炎的临床特征诊断及治疗方法。[方法]分析4例弥漫性泛细支气管炎患者临床表现、实验室检查、影像学、肺功能特点以及治疗效果。[结果]弥漫性小叶中心性结节3例,两肺弥漫性小叶中心性颗粒样结节状阴影合并广泛支气管扩张1例。4例患者鼻窦CT均提示副鼻窦炎,2例合并鼻息肉。肺功能检查3例患者呈阻塞性通气功能障碍,1例呈混合性通气功能障碍;4例FEV1/FVC(一秒钟用力呼气容积/用力肺活量)均70%。4例经过大环内酯类药物3～6个月后均取得较好的疗效。[结论]弥漫性泛细支气管炎可根据病史、临床表现、影像学及肺组织活检进行诊断,及时使用红霉素等大环内酯类药物治疗则可以阻止病变进展,改善预后。

Clinical Analysis of Diffuse Panbronchiolitis in 4 Patients

[Objective]To approach the clinical feature,diagnosis and treatment of diffuse panbronchiolitis.[Method]We reported the diffuse panbronchiolitis(DPB)in 4 patients and analysed the clinical manifestations,related lab test result,pulmonany function,imaging manifestations and treatment effects.[Result]Pulmonary high resolution computed tomography showed diffuse nodular pattern in three cases,and bronchiectasis in another case;Nasal cavity CT of all four patients showed accessory sinusitis,and two of these had ...