EFFECT OF SURGERY ON SENSORY THRESHOLD AND SOMATOSENSORY EVOKED POTENTIALS AFTER SKIN STIMULATION |
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| Authors: | LUND, C. HANSEN, O. B. KEHLET, H. |
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| Affiliation: | Department of Anaesthesiology, Hvidovre University Hospital Kettegárd alle 30, DK-2650 Hvidovre, Denmark
Department of Surgical Gastroenterology, Hvidovre University Hospital Kettegárd alle 30, DK-2650 Hvidovre, Denmark |
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| Abstract: | We have studied the effect of surgical injury on cutaneous sensitivityand somatosensory evoked potentials (SSEP) to dermatomal electricalstimulation in 10 patients undergoing hysterectomy. Forty-eighthours after surgery, sensory threshold increased from 2.2 (SEM0.3) mA to 4.4 (1.1) mA (P < 0.01) and SSEP amplitudes inP1, N1, P2 and the peak-to-peak amplitudes decreased (P <0.05). Latency was prolonged only in the N3 component (P <0.05). No changes were seen in threshold and SSEP in a controlgroup studied over the same interval. The results suggest thatsurgical injury activates antinociceptive modulatory systems. |
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