| 放射免疫治疗中的α核素微剂量研究 |
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| 引用本文： | 田源,张良安. 放射免疫治疗中的α核素微剂量研究[J]. 国际放射医学核医学杂志, 2006, 30(1): 39-41 |
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| 作者姓名： | 田源 张良安 |
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| 作者单位： | 300192 天津, 中国医学科学院中国协和医科大学放射医学研究所保健物理研究室 |
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| 摘 要： | 微剂量研究在临床α核素放免治疗的计划设计和疗效评价中起重要作用。设计一整套既能准确描述α粒子在细胞、亚细胞水平上剂量的不均匀分布,又适于临床使用的微剂量估算模型,一直是该领域的重要研究内容。本文介绍了α核素微剂量计算的几种常用方法以及最新发现的显著影响其结果精确度的因素。
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| 关 键 词： | α粒子 放射免疫治疗 微剂量 |
| 文章编号： | 1673-4114(2006)01-0039-03 |
| 收稿时间： | 2005-03-28 |
| 修稿时间： | 2005-03-28 |
A review of microdosimetric study in alpha particle radioimmunotherapy |
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| TIAN Yuan,ZHANG Liang-an. A review of microdosimetric study in alpha particle radioimmunotherapy[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2006, 30(1): 39-41 |
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| Authors: | TIAN Yuan ZHANG Liang-an |
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| Affiliation: | Department of Health Physics, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China |
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| Abstract: | Microdosimetry plays an important role in the clinical application of alpha-particle radioimmunotherapy. There is increasing interest to develop a set of microdosimetric model, which can exactly describe the nonuniformly distribution of dose at cellular or sub-cellular level as well as can be conveniently used in clinic. In this paper, introduce some common methods of microdosimetry and some important affective factors reported in current researches on alpha-particle radioimmunotherapy. |
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| Keywords: | α-Particle Radioimmunotherapy Microdosimetry |
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