Fournier's gangrene and scrotal ulcerations during all-trans-retinoic acid therapy for acute promyelocytic leukemia |
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Authors: | Naithani Rahul Kumar Rajat Mahapatra M |
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Affiliation: | Department of Hematology, All India Institute of Medical Sciences, New Delhi, India. dr_rahul6@hotmail.com |
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Abstract: | Scrotal ulcers are a rare manifestation in patients with acute promyelocytic leukemia. Fournier's gangrene (FG) is even rarer. We describe three adolescents and young adults who developed scrotal ulcerations during induction with all-trans-retinoic acid. One patient developed FG. These lesions are predominantly seen in Asian population. A good outcome with supportive management occurred in all the cases. |
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Keywords: | APL ATRA Fournier's gangrene scrotal ulcers |
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