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山慈菇Cremastra appendiculata化学成分
引用本文:薛震,李帅,王素娟,杨永春,贺定祥,冉光伦,孔令忠,石建功.山慈菇Cremastra appendiculata化学成分[J].中国中药杂志,2005,30(7):511-513.
作者姓名:薛震  李帅  王素娟  杨永春  贺定祥  冉光伦  孔令忠  石建功
作者单位:1. 中国医学科学院,中国协和医科大学,药物研究所,北京,100050
2. 贵州省黔东南州信邦中药饮片有限责任公司,贵州,黔东南,556000
摘    要:目的:研究人工种植山慈菇的化学成分。方法:采用硅胶柱色谱法分离纯化,薄层色谱比较及波谱法进行结构鉴定。结果:从山慈菇乙醇提取物的醋酸乙酯萃取部分中分离得到6个化合物,鉴定为异赫尔西酚(isohircinol,Ⅰ),4甲氧基菲-2,7-二醇(flavanthrinin,Ⅱ),对羟基苯乙醇(phydroxyphenylethylalcohol,Ⅲ),3,4-二羟基苯乙醇(3,4-dihydroxyphenylethylalcohol,Ⅳ),胡萝卜苷(daucosterol,Ⅴ),β-谷甾醇(β-sitosterol,Ⅵ)。结论:化合物Ⅱ~Ⅵ为首次从该植物中分离得到,化合物Ⅰ为首次从天然资源中分离得到。

关 键 词:山慈菇  化学成分
文章编号:1001-5302(2005)07-0511-03
收稿时间:8/5/2004 12:00:00 AM

Studies on chemical constituents from the corm of Cremastra appendiculata
XUE Zhen ;LI Shuai ;WANG Su-juan ;YANG Yong-chun ;HE Ding-xiang ;RAN Guang-lun ;KONG Ling-zhong ;SHI Jian-gong.Studies on chemical constituents from the corm of Cremastra appendiculata[J].China Journal of Chinese Materia Medica,2005,30(7):511-513.
Authors:XUE Zhen ;LI Shuai ;WANG Su-juan ;YANG Yong-chun ;HE Ding-xiang ;RAN Guang-lun ;KONG Ling-zhong ;SHI Jian-gong
Institution:Institute of Materia Medica, Chinese Academy of Medial Sciences, Being 100050, China.
Abstract:OBJECTIVE: To study the chemical constituents of the corm of the planted Cremastra appendiculata. METHOD: The compounds were isolated by column chromatography with silica gel and Sephadex LH-20, and their structures were elucidated by means of spectroscopic methods including 2D NMR techniques. RESULT: Six compounds were isolated, and identified as isohircinol (I), flavanthrinin (II), p-hydroxyphenylethyl alcohol (III), 3,4-dihydroxyphenylethyl alcohol (IV), daucosterol (V), beta-sitosterol (VI). CONCLUSION: These compounds were not previously isolated from this plant, and isohircinol (I) was obtained from natural source for the first time.
Keywords:Cremastra appendiculata  chemical constituents
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