应用氯诺昔康与曲马多术后自控静脉镇痛的比较

目的　比较氯诺昔康和曲马多对病人术后自控镇痛的效果与优缺点。方法　选择 1 0 0例胆囊炎、胆石症患者施胆囊切除术 ,ASAⅠ～Ⅱ级。随机分为A、B 2组 ,每组各 5 0例 ,术后经外周静脉通路连PCIA ,A组首剂量用氯诺昔康 4mg ,B组用曲马多 1 0 0mg ,连续量为 2mL/h ,自控量为 0 5mL/ 1 5min。A组PCIA用氯诺昔康 4 4～ 5 6mg ,氟哌利多 5mg ;B组用曲马多 1 0 0 0～ 1 2 0 0mg ,氟哌利多 5mg ,均稀释成 1 0 0mL ,分别于术后 4、8、1 2、2 4、4 8和 72h观察各时相的指标。结果　 2组镇痛效果无显著差异 ,生命体征平稳 ,不良反应A组较B组反应少。结论　氯诺昔康做为曲马多PCIA的替代药物 ,镇痛效果相当 ,但不良反应较少

Comparisom on Patient Control Intravenous Analgesia with Lornoxican and Tramadol

Objective To compare the analgesia effect and advantage of lornoxican and tramadol with Patient Control Intravenous Analgesia (PCIA). Methods 100 cases of cholecystectomy patient were divided into group A and group B in ASAI-II . 44～56 mg lornoxican and 5 mg droperidol in group A and 1000～1200 mg tramadol and 5 mg droperidol in group B were used in PCIA. The data of 4, 8, 12, 24, 48, and 72 h after operation was observed. Results There was no difference in analgesia effect between two groups with stable signs. But side effect was less in group A than that in group B. Conclusion Lornoxican as substitute of tramadol could reach same analgesia effect and less side effect than tramadol.