| 组织工程方法修复缺损面肌的初步研究 |
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| 引用本文： | 黄桂林,李龙江,李华林. 组织工程方法修复缺损面肌的初步研究[J]. 遵义医学院学报, 2002, 25(1): 9-11 |
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| 作者姓名： | 黄桂林 李龙江 李华林 |
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| 作者单位： | 1. 遵义医学院附属口腔医院,口腔颌面外科,贵州,遵义,563003
2. 四川大学华西口腔医院,口腔颌面外科,四川,成都,610044 |
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| 基金项目： | 贵州省自然科学基金资助项目(No:2001-3090). |
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| 摘 要： | 目的 进行成肌细胞的组织工程化 ,探讨面肌缺损功能性修复的可能性。方法 分离、差速贴壁法纯化、传代培养SD新生鼠成肌细胞并与I型胶原海绵复合培养成组织工程块 ,植入同种成年鼠体内。结果 工程化的成肌细胞在体外培养生长分化良好 ,动物体内存活并形成肌小管 ,肌块内见血管、神经生长。结论 组织工程化肌组织可能成为面肌功能性修复的人工仿真材料。
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| 关 键 词： | 成肌细胞 组织工程 面肌 功能修复 |
| 文章编号： | 1000-2715(2002)01-0009-03 |
Preliminary functional reconstruction with tissue engineered myoblast in facial muscle of rat |
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| HUANG Gui-lin ,LI Long-jian ,LI Hua-lin. Preliminary functional reconstruction with tissue engineered myoblast in facial muscle of rat[J]. Acta Academiae Medicine Zunyi, 2002, 25(1): 9-11 |
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| Authors: | HUANG Gui-lin LI Long-jian LI Hua-lin |
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| Affiliation: | HUANG Gui-lin 1,LI Long-jian 2,LI Hua-lin 1 |
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| Abstract: | Objective Reconstruction of facial muscle defects with tissue engineered myoblast in SD rats is discussed Methods Purified subcultured myoblast of neonatal rat and type I collagen gels as ECM Tissue engineered muscle was transplanted in the face of syngeneic mutured rats Results Tissue engineered myoblast fused with each other and formed myotube in face of rats, nerve fibre in some cases and vessel regeneration could be found Conclusions Tissue engineered myoblast may be as a new method to reconstruct defects of facial muscle with further research. |
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| Keywords: | Myoblast Tissue engineering Facial muscle Functional reconstruction |
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