Hypokaliemic periodic paralysis and pregnancy: perinatal management. A case report |
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Authors: | Parant O Grandjean S Castagno R Letourneur B Desprats R Larrue V |
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Institution: | Services de gynécologie-obstétrique, CHU Paule-de-Viguier, 330, avenue de Grande-Bretagne, TSA 70034, 31059 Toulouse cedex 09, France. olivier.parant@wanadoo.fr |
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Abstract: | Familial hypokalemic periodic paralysis (FHPP) is a rare inherited disease characterized by a dysfunction of the membrane ion channels. Clinical manifestations are attacks of hypokaliemia with flaccid muscle paralysis. Paralysis is sometimes severe but always reversible with symptomatic treatment. Pregnancy and delivery have been reported to exacerbate FHPP. Authors report a case of FHPP during pregnancy with a favourable outcome. Vaginal delivery is usually possible with monitoring and epidural analgesia, avoiding active maternal expulsive efforts (passive descent of the fetus and elective outlet forceps) and other stimulating factors (carbohydrate loads, maternal stress, betamimetics, epinephrine...). Administration of IV potassium supplementation is often necessary. |
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Keywords: | Paralysie périodique hypokaliémique Complication de la grossesse Accouchement Anesthésie |
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