Greater hand-grip strength predicts a lower risk of developing type 2 diabetes over 10 years in leaner Japanese Americans |
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Authors: | Wander P L Boyko E J Leonetti D L McNeely M J Kahn S E Fujimoto W Y |
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Institution: | a Department of Medicine, University of Washington, Seattle, WA, United States b VA Puget Sound Health Care System, Seattle, WA, United States c Department of Anthropology, University of Washington, Seattle, WA, United States |
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Abstract: | AimsMuch is known about body composition and type 2 diabetes risk but less about body function such as strength. We assessed whether hand-grip strength predicted incident diabetes.MethodsWe followed 394 nondiabetic Japanese-American subjects (mean age 51.9) for the development of diabetes. We fit a logistic regression model to examine the association between hand-grip strength at baseline and type 2 diabetes risk over 10 years, adjusted for age, sex, and family history.ResultsA statistically significant (p = 0.008) and negative (coefficient −0.208) association was observed between hand-grip strength and diabetes risk that diminished at higher BMI levels. Adjusted ORs for a 10-pound hand-grip strength increase with BMI set at the 25th, 50th or 75th percentiles were 0.68, 0.79, and 0.98, respectively.ConclusionsAmong leaner individuals, greater hand-grip strength was associated with lower risk of type 2 diabetes, suggesting it may be a useful marker of risk in this population. |
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Keywords: | Epidemiology Muscle Hand strength Japanese-American |
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