Effects of patulin on adenosine triphosphatase activities in the mouse.期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Effects of patulin on adenosine triphosphatase activities in the mouse.

Authors:	T D Phillips A W Hayes

Affiliation:	Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi 39216 USA

Abstract:	Patulin (4-hydroxy-4H-furol3,2clpyran-2(6H)-one), a toxic metabolite of various species of Aspergillus and Penicillium, differentially inhibited (in vitro) the Na⁺ $/>K<sup>+</sup>-activated and the oligomycin-sensitive and insensitive Mg<sup>2+</sup>-adenosine triphosphatase activities of mouse brain, kidney, and liver fractions containing nerve endings, mitochondria, and endoplasmic reticulum (B), and microsomal preparations (C) from these tissues. A dose-dependent inhibition of Na<sup>+</sup><img style=$
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