Hypothesis: reduced renal mass with glomerular hyperfiltration,a cause of renal hyperechogenicity in children |
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Authors: | E F Avni M -L Van Sinoy M Hall B Stallenberg C Matos |
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Institution: | (1) Department of Radiology, Erasme Hospital (ULB), Route de Lennik, 808, B-1070 Brussels, Belgium |
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Abstract: | A group of 10 pediatric patients had renal hyperechogenicity and reduced renal mass. The authors wish to suggest a relationship
between renal hyperechogenicity and glomerular hyperfiltration according to Brenner's theory on the progressive nature of
kidney disease. Reduced renal mass was related to multicystic dysplastic kidney (3 cases) nephrectomy (3 cases) and to reflux
nephropathy (4 cases). The hyperechogenicity was diffuse in 6 cases with the preservation of cortico-medullary differentiation
and was localized in all four cases of reflux nephropathy producing a “pseudotumoral” appearance. Hyperfiltration was confirmed
by isotope studies in all 3 cases where it was performed. This condition together with secondary glomerulosclerosis could
explain hyperechogenicity. The predicitive value of such patterns are still unclear; yet such findings should lead to appropriate
radiolocal, functional, clinical and dietary measures.
Presented at the ESPR/Meeting Montreux 1988. Selected for Publication by an International Group of the ESPR |
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