| 麻杏石甘汤治疗支气管哮喘的药效学研究 |
| |
| 引用本文： | 梁文能,丘振文,王沛坚. 麻杏石甘汤治疗支气管哮喘的药效学研究[J]. 时珍国医国药, 2007, 18(8): 1949-1950 |
| |
| 作者姓名： | 梁文能 丘振文 王沛坚 |
| |
| 作者单位： | 1. 广州中医药大学第一附属医院,广东,广州,510405
2. 广州中医药大学,广东,广州,510405 |
| |
| 摘 要： | 目的研究麻杏石甘汤治疗支气管哮喘的药效学。方法采用豚鼠磷酸组胺引喘实验、二甲苯致小鼠耳廓肿胀实验、氨水引起的小鼠咳嗽、小鼠气管酚红法等进行研究。结果实验组能增强豚鼠对磷酸组胺所致哮喘的抵抗力;抑制二甲苯所致小鼠耳廓肿胀;抑制氨水引起的小鼠咳嗽;增强小鼠气管酚红分泌量,与阴性对照组比较,有显著性差异(P<0.01或P<0.05)。与阳性对照组比较,多数指标无显著性差异(P>0.05)。结论麻杏石甘汤具有良好的抗支气管哮喘的作用,应进一步深入探讨其治疗哮喘的作用机制。
|
| 关 键 词： | 麻杏石甘汤 支气管哮喘 药效学 |
| 文章编号： | 1008-0805（2007）08-1949-02 |
| 收稿时间： | 2006-12-12 |
| 修稿时间： | 2006-12-122007-03-26 |
Experimental Study on the Effect of MaxingShigan Composition on Bronchial Asthma |
| |
| LIANG Wen-neng,QIU Zhen-wen,WANG Pei-jian. Experimental Study on the Effect of MaxingShigan Composition on Bronchial Asthma[J]. Lishizhen Medicine and Materia Medica Research, 2007, 18(8): 1949-1950 |
| |
| Authors: | LIANG Wen-neng QIU Zhen-wen WANG Pei-jian |
| |
| Affiliation: | 1. The First Affiilated Hospital of Guangzhou University of TCM, Guangzhou 510405, China; 2. Guangzhou University of TCM, 510405, China |
| |
| Abstract: | Objective To investigate the therapeutic effect of Maxingshigan Composition on Bronchial Asthma.Methods Adopt phosphonic acid and histamine to evoke cobaya asthma.To use the dimethyl benzene induce the musculus albus aures engorgement.To use ammonia water to induce cough.The method of mouse phenolsulfonphthalein was also used.All above methods were to investigate the therapeutic effect of Maxingshigan Composition.Results Maxingshigan Composition could enhance cobaya's anti-asthma ablility,depress the mice's auricular tumefaction,depress the mice's on cough caused by histamine phosphate,increase excretory rate of the phenolsulfonphthalein.Curing effect of Maxingshigan Composition was shown to be superior to that in the blank group(P<0.01or P<0.05).Conclusion The drug plays a significant role in curing asthma,increasing the resistance to anoxia and fatigue,and has anti-inflammatory effect. |
| |
| Keywords: | Maxingshigan Composition Bronchial asthma Pharmacodynamics |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
