Efficacy of Percutaneous Vascular Hemostasis System Prostar: Comparison to Manual Compression

In this study, we evaluated the safety and efficacy of the percutaneous vascular surgery device (Prostar) for sealing the femoral artery puncture site after coronary interventions. We also compared the results with Prostar (n = 167) and conventional manual compression methods (n = 50) in a nonrandomized fashion. The average time to hemostasis in the Prostar system group was 13.5 minutes, versus 36.6 minutes in the compression group. The average time to ambulation was 2.2 hours in the Prostar system group, versus 17.8 hours in the manual group. Bleeding was observed in 1.2% of the subjects in the Prostar system group, versus 12% in the manual compression group. One emergency surgery was required in the manual compression group, whereas no surgical intervention was required in the Prostar group. We conclude that the Prostar system for percutaneous vascular closure appears to be a safe technique for achieving an early hemostasis and ambulation after coronary intervention.