| 同种异体肌腱移植重建前交叉韧带的免疫排斥反应 |
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| 引用本文： | 左健,孙皓,潘乐.同种异体肌腱移植重建前交叉韧带的免疫排斥反应[J].中国组织工程研究与临床康复,2011,15(53). |
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| 作者姓名： | 左健 孙皓 潘乐 |
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| 作者单位： | 石家庄学院体育系,河北省石家庄市,050035 |
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| 摘 要： | 背景:近年来同种异体肌腱移植逐渐用于治疗膝关节前交叉韧带损伤.目的:综述膝关节前交叉韧带损伤的特点及其同种异体肌腱移植重建后的免疫排斥反应问题.方法:应用计算机检索1990-01/2011-10 PubMed数据库及维普数据库相关文献.英文检索词"anterior cruciate ligament,allograft,anatomy,transplantation",中文检索词"前交叉韧带,同种,肌腱,移植".检索文献量总计164篇,最终纳入符合标准的文献34篇.结果与结论:国内外学者对同种异体肌腱移植重建前交叉韧带进行了几十年的研究,已逐步了解了膝关节前交叉韧带的生物力学特性;通过冷冻处理法、细胞毒物质处理法解决了同种异体肌腱移植后的免疫排斥反应,使其既能降低异体肌腱的抗原性,又能保存肌腱细胞的活性,促使肌腱的内源性愈合,提高肌腱愈合速度与强度,减轻或避免肌腱粘连的发生,临床应用取得了很好的效果.
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| 关 键 词： | 前交叉韧带 同种 肌腱 移植 综述文献 |
Immune rejection following anterior cruciate ligament reconstruction with tendon allograft |
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| Zuo Jian,Sun Hao,Pan Le.Immune rejection following anterior cruciate ligament reconstruction with tendon allograft[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2011,15(53). |
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| Authors: | Zuo Jian Sun Hao Pan Le |
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| Institution: | Zuo Jian,Sun Hao,Pan Le Department of Physical Education,Shijiazhuang University,Shijiazhuang 050035,Hebei Province,China |
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| Abstract: | BACKGROUND: In recent years, tendon allograft is gradually used for repair of anterior cruciate ligament injury. OBJECTIVE: To review the characteristics of anterior cruciate ligament injury and immune rejection following anterior cruciate ligament reconstruction with tendon allograft. METHODS: A computer-based search of PubMed and VIP databases (1990-01/2011-10) was performed for relevant articles using the keywords of anterior cruciate ligament, allograft, anatomy, transplantation in English and anterior ... |
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