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| ABO血型不合外周血造血干细胞移植10例 | |
| 引用本文： | 金哈斯,鲁燕侠,陶格斯花,龚丽萍,母立新.ABO血型不合外周血造血干细胞移植10例[J].中国组织工程研究与临床康复,2011,15(40). |
| 作者姓名： | 金哈斯 鲁燕侠 陶格斯花 龚丽萍 母立新 |
| 作者单位： | 1. 武警总医院血液科,北京市,100039 2. 内蒙古乌拉特前旗中蒙医院,内蒙古自治区巴彦淖尔市,014400 3. 首都医科大学病理系,北京市,100612 4. 首都机场医院外科,北京市,100090 |
| 摘 要： | 背景:ABO血型不合供受者之间进行外周血造血干细胞移植,面临受者血型的转变、移植后输血的选择等问题.目的:观察ABO血型不合外周血造血干细胞移植治疗血液病的临床疗效和近远期并发症.方法:回顾性分析了2005/2008武警总医院收治的10例ABO血型不合异基因外周血同胞供者造血干细胞移植患者的资料.总结植入效果,血型转变,移植物抗宿主病以及不良反应.结果与结论:9例患者恢复造血功能,血型转变为完全供者型,1例患者白细胞血小板恢复,但红细胞植入延迟.所有患者在输注移植物时未出现短暂的血红蛋白尿,无严重急性溶血和迟发型溶血的发生,1例出现严重的移植物抗宿主病.可见ABO血型不合外周血造血干细胞移植对移植疗效无明显影响,红细胞植入延迟的预防和处理十分重要. |
| 关 键 词： | 造血干细胞 细胞移植 ABO血型系统 血型不合 溶血 |
ABO-incompatible peripheral hematopoietic stem cell transplantation in 10 cases |
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| Jin Ha-si,Lu Yan-xia,Tao Ge Si Hua,Gong Li-ping,Mu Li-xin.ABO-incompatible peripheral hematopoietic stem cell transplantation in 10 cases[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2011,15(40). | |
| Authors: | Jin Ha-si Lu Yan-xia Tao Ge Si Hua Gong Li-ping Mu Li-xin |
| Institution: | Jin Ha-si1,Lu Yan-xia1,Tao Ge Si Hua2,Gong Li-ping3,Mu Li-xin4 1Department of Hematology,General Hospital of Armed Police Forces,Beijing 100039,China,2Zhong Meng Hospital of Wulate Qian Qi,Bayan Nur 014400,Inner Mongolia Autonomous Region,3Department of Pathology,Capital Mediacl University,Beijing 100612,4Capital Airport Hospital,Beijing 100090 |
| Abstract: | BACKGROUND: During ABO-incompatible peripheral hematopoietic stem cell transplantation, it is very important to observe the change of blood type of patients and to select correct blood type in transfusion. OBJECTIVE: To observe the clinical effect and short-term and long-term complications in ABO-incompatible allogeneic peripheral hematopoietic stem cell transplantation. METHODS: Ten patients after ABO-incompatible peripheral hematopoietic stem cell transplantation were enrolled between 2005 and 2008. Trans... |
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