| 成体干细胞与肺重建 |
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| 引用本文： | 苏申,孙海燕,张彤,吴丽君,姚济荣.成体干细胞与肺重建[J].中国组织工程研究与临床康复,2011,15(45). |
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| 作者姓名： | 苏申 孙海燕 张彤 吴丽君 姚济荣 |
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| 作者单位： | 首都医科大学附属北京世纪坛医院神经内科,北京市,100038 |
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| 基金项目： | 国家自然科学基金(81100366)~~ |
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| 摘 要： | 背景:肺组织结构复杂,病变周期长,具有主动归巢与调控功能的干细胞植入的治疗手段具有巨大的应用前景.目的:全面了解成体干细胞治疗肺疾病与损伤的研究进展.方法:由第一作者检索Pubmed数据库中2011年前发表的有关成体干细胞与肺损伤,多系分化及组织重建等方面的文章,排除重复性研究.结果与结论:共检索到135篇相关文献,保留其中50篇进行综述.研究表明以骨髓来源的间充质干细胞为代表的成体干细胞具有较强的多系分化潜能,可用于治疗肺部疾病,可参与损伤修复甚至组织再生.其治疗机制及相关影响因素还有待进一步研究.
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| 关 键 词： | 肺 成体干细胞 干细胞移植 肺损伤 重建 |
Adult stem cells and lung regeneration |
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| Su Shen,Sun Hai-yan,Zhang Tong,Wu Li-jun,Yao Ji-rong.Adult stem cells and lung regeneration[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2011,15(45). |
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| Authors: | Su Shen Sun Hai-yan Zhang Tong Wu Li-jun Yao Ji-rong |
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| Institution: | Su Shen,Sun Hai-yan,Zhang Tong,Wu Li-jun,Yao Ji-rong Department of Neurology,Beijing Shijitan Hospital of Capital Medical University,Beijing 100038,China |
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| Abstract: | BACKGROUND:Stem cells with active homing function and regulation has a great application prospect to lung regeneration due to the lung tissue with complex structure and long disease cycle.OBJECTIVE:To overally understand the progress of adult stem cells in treatment of lung diseases and injury.METHODS:The first author retrieved PuMed for articles about adult stem cells for lung injury published before 2011.Repetitive articles were excluded.RESULTS AND CONCLUSION:Totally 135 articles were retrieved,and final... |
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