| 人工真皮修复急性创伤后足背皮肤软组织缺损14例 |
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| 引用本文： | 王浩,陈欣.人工真皮修复急性创伤后足背皮肤软组织缺损14例[J].中国组织工程研究与临床康复,2011,15(42). |
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| 作者姓名： | 王浩 陈欣 |
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| 作者单位： | 北京积水潭医院烧伤整形科,北京市,100035 |
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| 摘 要： | 背景:人工真皮具有硅胶膜和胶原海绵双层结构,是最早开发和应用于临床的组织工程化皮肤替代物,主要应用于皮肤软组织缺损修复.目的:评价人工真皮在足背严重皮肤软组织缺损中的应用.方法:选择北京积水潭医院烧伤科于2009-06/2010-12收治的14例急性外伤后足背严重皮肤软组织缺损患者,均有肌腱或骨外露.所有患者经清创后,以人工真皮移植,待人工真皮成活后以自体断层皮片移植,观察人工真皮和自体皮的成活情况.结果与结论:所有植皮成活,创面愈合良好,供区未见明显瘢痕增生.提示人工真皮联合自体断层皮片移植可以有效修复足背严重皮肤缺损创面,减少供区损伤.
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| 关 键 词： | 人工真皮 足背 组织缺损 骨外露 瘢痕 生物材料 |
Repair of acute traumatic soft tissue defects of foot with artificial dermis in 14 cases |
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| Wang Hao,Chen Xin.Repair of acute traumatic soft tissue defects of foot with artificial dermis in 14 cases[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2011,15(42). |
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| Authors: | Wang Hao Chen Xin |
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| Institution: | Wang Hao,Chen Xin Department of Burn and Plastic Surgery,Beijing Jishuitan Hospital,Beijing 100035,China |
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| Abstract: | BACKGROUND: Artificial dermis has a bilayer structure of collagen sponge and silicone layer, which has been developed and successfully applied in clinics. It is commonly used for the repair of defects of skin and soft tissue. OBJECTIVE: To study and appraise the application of artificial dermis in repairing severe defect of skin and soft tissue of foot. METHODS: A total of 14 patients were admitted at the Department of Burn and Plastic Surgery, Beijing Jishuitan Hospital from June 2009 to December 2010, and... |
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