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2Hz极低频脉冲电磁场可促进金属植入物内固定四肢新鲜骨折的愈合
引用本文:刘纪涛,陶军. 2Hz极低频脉冲电磁场可促进金属植入物内固定四肢新鲜骨折的愈合[J]. 中国组织工程研究与临床康复, 2011, 15(52). DOI: 10.3969/j.issn.1673-8225.2011.52.004
作者姓名:刘纪涛  陶军
作者单位:南昌大学第三附属医院骨一科,江西省南昌市,330008
基金项目:2009~2010年度江西省卫生厅科技计划项目(20093164)资助~~
摘    要:背景:骨折内固定后易发生骨延迟愈合及骨不愈合.目的:观察金属植入物骨折内固定后联合不同极低频率脉冲电磁场治疗四肢新鲜骨折的疗效.方法:将四肢新鲜骨折患者随机分为4组,对照组内固定后给予常规治疗,其他3组内固定后第3天起分别配合2,16,32 Hz脉冲电磁场治疗,4组患者分别于内固定后4,8,12周行骨折部位的X射线检查,固定前及固定后联合脉冲电磁场治疗完成时,分别检测4组患者骨钙素、骨特异性碱性磷酸酶水平及Ⅰ型前胶原羧基末端前肽,并进行疗效评定.结果与结论:随治疗时间延长,4组骨痂生成均增多(P < 0.01);在相同时间点上,2,16,32 Hz治疗组骨痂生成情况及骨代谢生化指标均明显高于对照组(P < 0.01);2 Hz治疗组骨痂生成情况及骨代谢生化指标均高于16,32 Hz治疗组(P < 0.05).结果证实,脉冲电磁场促进骨痂生长从而促进骨折愈合,2 Hz极低频脉冲电磁场促进金属植入物内固定骨折愈合的疗效优于16,32 Hz.

关 键 词:脉冲电磁场  骨折  愈合  疗效  金属植入物  骨组织工程

A 2 Hz extremely low-frequency pulsed magnetic field promotes the healing of fresh limb fractures following metallic implants internal fixation
Liu Ji-tao,Tao Jun. A 2 Hz extremely low-frequency pulsed magnetic field promotes the healing of fresh limb fractures following metallic implants internal fixation[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2011, 15(52). DOI: 10.3969/j.issn.1673-8225.2011.52.004
Authors:Liu Ji-tao  Tao Jun
Affiliation:Liu Ji-tao,Tao Jun First Department of Orthopaedics,Third Affiliated Hospital of Nanchang University,Nanchang 330008,Jiangxi Province,China
Abstract:BACKGROUND: Delayed bone healing and nonunion are prone to occur after fracture treated with internal fixation. OBJECTIVE: To study the clinical effects of the pulsed magnetic fields (PEMFs) of different extremely low-frequency for treatment of fresh fracture of limbs after internal fixation with metallic implants. METHODS: The patients with fresh fractures of the limbs were divided into four groups randomly. The patients of control group were treated with routine therapy and the patients of treatment group...
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