| Quantitative Study on Expression of P16 Multiple Tumor Suppressor Gene in Salivary Gland Neoplasm |
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| 引用本文： | 朱声荣,王秀丽,邵乐南,陈卫民,陈新明,吴慧华. Quantitative Study on Expression of P16 Multiple Tumor Suppressor Gene in Salivary Gland Neoplasm[J]. 华中科技大学学报(医学英德文版), 1999, 19(2): 155-157. DOI: 10.1007/BF02886899 |
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| 作者姓名： | 朱声荣 王秀丽 邵乐南 陈卫民 陈新明 吴慧华 |
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| 作者单位： | ZHU Shengrong，WANG Xiuli，SHAO Lenan CHEN Weimin，CHEN Xinming *，WU Huihua Department of Stomatology，Tongji Hospital，Tongji Medical University，Wuhan 430030 * College of Stomatology，Hubei Medical University，Wuhan 430060 |
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| 摘 要： | ＷｅｂｅｌｉｅｖｅｉｔｉｓｏｆｇｒｅａｔｉｍｐｏｒｔａｎｔｔｏｕｎｄｅｒｓｔａｎｄｔｈｅｒｅｌａｔｉｏｎｓｈｉｐｂｅｔｗｅｅｎＰ１６ｇｅｎｅａｎｄｄｅｖｅｌｏｐｍｅｎｔｏｆｔｈｅｓａｌｉｖａｒｙｇｌａｎｄｔｕｍｏｒｓ，ｉｎｏｒｄｅｒｔｏｅｌｕｃｉｄａ...
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Quantitative study on expression of p16 multiple tumor suppressor gene in salivary gland neoplasm |
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| Zhu Shengrong,Wang Xiuli,Shao Lenan,Chen Weimin,Chen Xinming,Wu Huihua. Quantitative study on expression of p16 multiple tumor suppressor gene in salivary gland neoplasm[J]. Journal of Huazhong University of Science and Technology. Medical sciences, 1999, 19(2): 155-157. DOI: 10.1007/BF02886899 |
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| Authors: | Zhu Shengrong Wang Xiuli Shao Lenan Chen Weimin Chen Xinming Wu Huihua |
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| Affiliation: | ZHU Shengrong,WANG Xiuli,SHAO Lenan CHEN Weimin,CHEN Xinming *,WU Huihua Department of Stomatology,Tongji Hospital,Tongji Medical University,Wuhan 430030 * College of Stomatology,Hubei Medical University,Wuhan 430060 |
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| Abstract: | The expression of P16 gene were found in all 3 groups. The positive unit (PU) was higher in tumor group and cancer group than that in normal group ( P <0.01). Furthermore, the PU of P16 was stronger in cytoplasm than in nucleus. Malignant tumors and acini surrounding the tumor revealed strong positives and week positives respectively. The PU of P16 gene was higher in deep lobe of recurrent parotid neoplasm with incomplete capsule than that in shallow lobe of primary parotid neoplasm with complete capsule. Our findings suggests that P16 gene plays equally important role in the salivary gland tumors and tumors in other part of the body. |
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| Keywords: | salivary gland neoplasm P16 gene immunohistochemistry |
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