Use of an immunoglobulin G avidity test to discriminate between primary and secondary dengue virus infections |
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| Authors: | de Souza Vanda Akico Ueda Fick Fernandes Silvana Araújo Evaldo Stanislau Tateno Adriana Fumie Oliveira Olímpia M N P F Oliveira Renato Reis Pannuti Cláudio Sérgio |
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| Affiliation: | Laboratório de Virologia (LIMHC-52), Instituto de Medicina Tropical de São Paulo, Departamento de Moléstias Infecciosas e Parasitárias da Faculdade de Medicina, Universidade de São Paulo,1 Hospital Ana Costa, Santos, São Paulo, Brazil2 |
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| Abstract: | An enzyme-linked immunosorbent assay-based immunoglobulin G (IgG) antibody avidity test was evaluated by using sera from 57 patients with acute dengue infection. Overall, 55 of 57 patients were correctly classified (27 of 27 with primary dengue and 28 of 30 with secondary dengue). We conclude that the IgG avidity test can be useful for differentiating between acute, primary, and secondary dengue infections. |
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